Cyfra21-1 (Cytokeratin Fragment Antigen 21-1, KS19.1, KRT19, CK19)

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£422.00

SKU:: 369345
Reinheit:: Purified by Protein G affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Cyfra21-1 (KS19.1).
Klon:: 17D53
Format:: Supplied as a liquid in 0.1M sodium chloride, 15mM sodium azide
Weitere Details:: Ks 19.1 represents an excellent marker to discriminate glandular epithelial carcinoma from those of different origin. No reaction with hepatocellular carcinoma. Polypeptide reacting: Mr 40 000 polypeptide (keratin K19; formerly also designated cytokeratin 19) of human glandular epithelia. he epitope has been localized on aa317-333 (KAALEDTLAETEARFKS) of the alpha-helical fragment.Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:500-1:5000 Immunohistochemistry (Parafffin): 1:50-1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.