369075
Igfbp6, Recombinant, Mouse, aa26-238, His-Tag (Insulin-like Growth Factor-binding Protein 6)
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£607.00
- SKU:
- 369075
- Molekulargewicht:
- 23.7
- Reinheit:
- ≥90% (SDS-PAGE). Endotoxin: ≤1EU/1ug (LAL)
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Format:
- Supplied as a liquid in PBS, pH 7.4, 40% glycerol.
- Weitere Details:
- Igfbp6, also known as insulin-like growth factor-binding protein 6, binds insulin-like growth factor 1(IGF-1) and IGF-2 with high affinity and inhibits IGF action in vitro. It is a cysteine-rich protein with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. It plays a key role in the regulation of IGF bioavailability, by modulating its molecular size, capillary membrane permeability, target tissue specificity, cell membrane adherence and IGF affinity. Source: Recombinant protein corresponding to aa26-238 from mouse Igfbp6, fused to His-Tag at C-terminal, expressed in insect cell. Amino Acid Sequence: ALAGCPGCGA GMQTGCRGGC VEEEDAGSPA DGCTEAGGCL RREGQPCGVY SPKCAPGLQC QPRENEEAPL RALLIGQGRC QRARGPSEET TKESKPQGGA SRSRDTNHRD RQKNPRTSAA PIRPNPVQDS EMGPCRRHLD SVLQQLQTEV FRGGARGLYV PNCDLRGFYR KQQCRSSQGN RRGPCWCVDP MGQPLPVSPD GQGSTQCSAR SSGLEHHHHH H Molecular Weight: ~23.7kD (221aa) 28-40kD (SDS-PAGE under reducing conditions) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice