368528
CD3E (CD3e Molecule, epsilon (CD3-TCR complex), IMD18, T3E, TCRE, CD3-epsilon, CD3e Antigen, epsilon Polypeptide (TiT3 complex), T-Cell Antigen Receptor Complex, epsilon Subunit of T3, T-Cell Surface Antigen T3/Leu-4 epsilon Chain, T-Cell Surface Glycoprorotein CD3 epsilon Chain)
Größe
£642.00
- SKU:
- 368528
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Goat
- Immunogen:
- Synthetic peptide corresponding to C-RKGQRDLYSGLNQR of human CD3E (NP_000724.1). Species sequence homology: rat, porcine
- Format:
- Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
- Weitere Details:
- The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms. Applications: Suitable for use in ELISA, Western Blot. Other applications not tested. Recommended Dilution: Peptide ELISA: 1:128,000 Western Blot: 0.3-1ug/ml, ~22kD band observed in lysates of cell lines Jurkat and Molt4 (calculated MW of 23.1kD according to NP_000724.1) Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice