TPX2 (Targeting Protein for Xklp2, Differentially Expressed in Cancerous and non-Cancerous Lung Cells 2, DIL-2, Hepatocellular Carcinoma-associated Antigen 519, Hepatocellular Carcinoma-associated Antigen 90, Protein fls353, Restricted Expression Proliferation-associated Protein 100, p100, TPX2, C20orf1, C20orf2, DIL2, HCA519)

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£384.00

SKU:: 366860
Reinheit:: Purified by Protein G affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to aa1-531 from human TPX2.
Klon:: 1696CT464.66.9
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Weitere Details:: Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:2000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.