AKAP13 (A-kinase Anchor Protein 13, AKAP-13, AKAP-Lbc, Breast Cancer Nuclear Receptor-binding Auxiliary Protein, Guanine Nucleotide Exchange Factor Lbc, Human Thyroid-Anchoring Protein 31, Lymphoid Blast Crisis Oncogene, LBC Oncogene, Non-oncogenic Rho GTPase-specific GTP Exchange Factor, Protein Kinase A-Anchoring Protein 13, PRKA13, p47, BRX, HT31, LBC)

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£384.00

SKU:: 366823
Reinheit:: Purified by Protein G affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: KLH-conjugated synthetic peptide mapping to a fragment of residues within aa18-170 from human AKAP13.
Klon:: 1742CT411.87.24
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Weitere Details:: Anchors cAMP-dependent protein kinase (PKA) and acts as an adapter protein to selectively couple G alpha-13 and Rho. Augments gene activation by the estrogen receptor in an element-specific and ligand-dependent manner. Activates estrogen receptor beta by a p38 MAPK-dependent pathway. Stimulates exchange activity on Rho proteins in vitro, but not on CDC42, Ras or Rac and may bind calcium ions. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:8000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.