365439
TRERF1 (Transcriptional Regulating Factor 1, BCAR2, TREP132, RAPA, Breast Cancer Anti-Estrogen Resistance 2, Transcriptional-regulating protein 132, Zinc finger protein rapa, Zinc finger transcription factor TReP-132)
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£537.00
- SKU:
- 365439
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa785-942 of mouse TRERF1, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Weitere Details:
- Transcriptional-regulating factor 1 is a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1.The deduced 1,200aa protein contains a glutamine-rich region, 2 proline-rich regions, an acidic region, and 3 C2H2-type zinc finger motifs. An alternatively spliced transcript with a longer 3-prime UTR encodes the same protein. Northern blot analysis detected transcripts of 4.4 and 7.5 kb abundantly expressed in thymus, testis, adrenal cortex, and a human choriocarcinoma cell line. Weak expression was detected in all other tissues examined except pancreas and small intestine. In vitro transcription and translation resulted in a protein with an apparent molecular mass of about 132kD, in agreement with the predicted size. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 5-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice