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365400

TOR1B (Torsin 1B, DQ1, Torsin ATPase-1B, Torsin family 1 member B)

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£537.00

SKU:
365400
Reinheit:
Purified by Protein A and peptide affinity chromatography.
Lagerbedingungen:
-20°C
Hersteller:
United States Biological
Host:
Rabbit
Immunogen:
Recombinant protein corresponding to aa83-327 of mouse TOR1B, expressed in E. coli.
Format:
Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Weitere Details:
By exon trapping on chromosome 9q34, screening fetal brain, adult frontal cortex, and adult liver cDNA libraries, and 5-prime and 3-prime RACE, Ozelius et al. (1997) cloned TOR1B, which they designated DQ1. The deduced 289aa protein has a calculated molecular mass of more than 32kD. TOR1B shares 69% amino acid identity with TOR1A, and both proteins contain an ATP-binding domain, 2 protein kinase C phosphorylation sites, a casein kinase II phosphorylation site, several N-myristoylation sites, and 6 conserved cysteines. Northern blot analysis detected expression of a 2.8-kb TOR1B transcript in adult brain, but not in fetal brain.TOR1B lies centromeric to TOR1A, and the 2 genes face in opposite orientations with their 3-prime ends about 2 kb apart. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 5-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Versandbedingungen:
Blue Ice