365271
TGFb1 (Transforming Growth Factor Beta 1, TGF-B1, CED, DPD1, LAP, Camurati-Engelmann Disease, Latency-associated peptide)
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£537.00
- SKU:
- 365271
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa279-390 of canine TGFb1, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
- Weitere Details:
- TGF-Beta is capable of producing a variety of effects and virtually all cell types respond to this factor in some way. The inappropriate presence of active TGF-Beta1 has been implicated in a variety of pathological conditions Because of the necessity for regulating its activity tightly, TGF-Beta is secreted by cells in the form of an inactive complex. This complex consists of TGF-Beta1 associated non-covalently with a protein designated the latency associated peptide (LAP). TGF-Beta1 and LAP represent components of a pro-peptide that is cleaved in a post-golgi compartment prior to secretion. LAP and TGF-Beta1 each consist of a disulfide-linked homodimer and the association of these two components renders TGF-Beta1 inactive and inaccessible to anti-TGF-Beta antibodies. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 5-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice