365082
SLC30A6 (Solute Carrier Family 30, Member 6, ZNT6, Zinc Transporter 6)
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£537.00
- SKU:
- 365082
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Val253-Pro458 of mouse SLC30A6, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Weitere Details:
- Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A6, permit cellular efflux of zinc. The deduced mouse and human proteins contain 460aa and share 92% identity. Mouse Znt6 has 6 transmembrane domains, a loop between transmembrane domains 4 and 5, and cytoplasmic N and C termini. In contrast to other Znt proteins, the loop region of Znt6 lacks multiple histidines. Normal rat kidney cells expressed Znt6 in a perinuclear location and in a punctate/tubular pattern throughout the cytoplasm and under the plasma membrane. Disruption of the Golgi compartment also disrupted Znt6 localization. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:50-400 Immunocytochemistry: 1:50-500 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 ELISA: 1:100-1:5000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice