365081
SLC30A5 (Solute Carrier Family 30, Member 5, ZTL1, ZnT-5, ZNT5, ZNTL1, Zinc Transporter 5, ZnT-like transporter 1)
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£537.00
- SKU:
- 365081
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa639-751 of mouse SLC30A5, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
- Weitere Details:
- The deduced 523aa protein contains 12 predicted membrane-spanning domains with extracellular N and C termini. Between transmembrane domains 9 and 10, ZTL1 has a zinc-binding histidine-rich intracellular loop. ZTL1 shares 34% identity with ZNT1 (SLC30A1) over a 122aa stretch, and it shares significant homology with several rodent zinc transporters. Northern blot analysis detected 2.0- and 5.0-kb transcripts in CaCo2 cell line RNA. RT-PCR of mouse tissues detected ubiquitous expression, with highest level in kidney and lowest level in liver. The deduced 765aa protein has 15 predicted membrane-spanning domains and a calculated molecular mass of about 84kD. Western blot analysis of the full-length protein expressed in HeLa cells indicated an apparent molecular mass of about 55kD. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 0.01-2ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice