365021
SEMA4D (Semaphorin 4D, CD100, A8, BB18, GR3, M-Sema G, M-Sema-G, SEMAJ, Coll-4, Sema Domain, Immunoglobulin Domain(Ig), Transmembrane Domain(TM)and Short Cytoplasmic Domain 4D)
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£524.00
- SKU:
- 365021
- Anwendung:
- WB
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Phe502-Phe636 of human SEMA4D expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Weitere Details:
- CD100 was first identified as a cell surface protein of resting T cells; previous studies had shown that it was involved in lymphocyte activation. Hall et al. (1996) cloned CD100 from a cDNA library of phytohemagglutinin-activated human T cells. Sequence analysis showed that CD100 encodes an 863aa polypeptide containing a secretory signal sequence, a single transmembrane domain, an immunoglobulin (Ig)-like domain, and a conserved 500aa sema domain. Thus, Hall et al. (1996) stated that CD100 is a member of the semaphorin family and the first semaphorin believed to be involved in the immune system. See SEMA3Fand SEMA3B. Northern blot analysis revealed that CD100 is expressed primarily as a 4.5-kb message in a variety of tissues, both hematopoietic and nonhematopoietic. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice