364874
RCBTB2 (RCC1 And BTB Domain Containing Protein 2 , CHC1L, RLG, RCC1-like G exchanging factor, Regulator Of Chromosome Condensation And BTB(POZ)Domain Containing Protein 2, Chromosome Condensation 1-Like)
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£517.00
- SKU:
- 364874
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Ala394-Leu519 of human RCBTB2, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Weitere Details:
- RCBTB2 encodes a member of the RCC1-related GEF family. The N-terminal half of the encoded amino acid sequence shows similarity to the regulator of chromosome condensation RCC1, which acts as a guanine nucleotide exchange factor (GEF) protein for the Ras-related GTPase Ran. The CHC1L gene contains 14 exons and spans at least 30 kb. The 3.2-kb CHC1L mRNA was expressed in all tissues tested by Northern blot analysis. The authors identified 4 alternatively spliced CHC1L transcripts encoding 2 protein isoforms of 551 and 526aa, respectively. Sequence analysis revealed that both isoforms contain 6 repeats that share homology with repeats found in CHC1 and RPGR, and a zinc finger motif. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice