364321
NCR3 (Natural Cytotoxicity Triggering Receptor 3, CD337, 1C7, LY117, NKp30, Lymphocyte Antigen 117, Activating natural killer receptor p30, Natural killer cell p30-related protein)
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£524.00
- SKU:
- 364321
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Ser22-Gly135 of human NCR3, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Weitere Details:
- Natural cytotoxicity receptors (NCRs), such as NCR3, are activating natural killer (NK) cell receptors that belong to the immunoglobulin (Ig) superfamily. NCR3 is expressed in all resting and activated NK cells and forms a complex with CD3-zeta (CD3Z, or CD247) The deduced 190aa protein has a signal peptide followed by a 120aa extracellular region that forms a V-type Ig-like domain with 2 potential N-linked glycosylation sites; a hydrophobic transmembrane region with a positively charged arg residue; and a 33aa cytoplasmic tail lacking an immunoreceptor tyrosine-based activating motif (ITAM). Northern blot analysis detected a 1.0-kb transcript only in NK cells. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice