364320
NCR2 (Natural Cytotoxicity Triggering Receptor 2, CD336, NCR2, LY95, NK-P44, NKP44, Lymphocyte Antigen 95, Activating NK-Receptor, NK cell-activating receptor, Natural killer cell p44-related protein)
Größe
£524.00
- SKU:
- 364320
- Reinheit:
- .
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Gln22-Ser120 of human NCR2 expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Weitere Details:
- LY95 is a member of the Ig superfamily. LY95 is a type I transmembrane protein with a 21aa leader sequence, a 169aa extracellular region, a 23aa transmembrane protein, and a 63aa cytoplasmic tail. The potential N- and O-linked glycosylation sites are apparently occupied since the observed molecular mass of LY95 is 44kD as opposed to the predicted 24kD. The cytoplasmic tail contains the amino acid sequence ILYHTV, which fits the consensus sequence for an immunoreceptor tyrosine-based inhibitory motif (ITIM). Northern blot analysis revealed that expression of 3.7- and 1.2-kb LY95 transcripts are restricted to interleukin-2 (IL2)-activated NK cell lines and clones. IL2-activated NK cells have enhanced activity in vitro and in vivo. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice