364219
MSRA (Methionine Sulfoxide Reductase A, PMSR, Peptide Methionine Sulfoxide Reductase, Protein-methionine-S-oxide reductase)
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£626.00
- SKU:
- 364219
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Ala27-Lys235 of human MSRA, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Weitere Details:
- Peptide methionine sulfoxide reductase is ubiquitous and highly conserved. It carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. MSRA mRNA is highly expressed in rat and human kidney, but to a lesser extent in other rat tissues. The highest specific activity of the mammalian MSRA enzyme was found in cell-free extracts prepared from rat kidney and human neutrophils. Neutrophils and macrophages are known to produce reactive oxygen species during a respiratory burst that kill invading bacteria during phagocytosis. It is suggested that MSRA functions to repair oxidative damage to proteins that may occur during oxidative bursts or other situations where reactive oxygen radicals exist. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice