364218
MSP (Macrophage Stimulating Protein, MST1, HGFL, NF15S2, Hepatocyte Growth Factor-Like Protein, Macrophage Stimulating 1)
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£505.00
- SKU:
- 364218
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Val489-Glu716 of rat MSP, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Weitere Details:
- MST1 cDNA from a human liver cDNA library. The deduced protein contains 4 kringle domains followed by a serine protease domain. Because this domain structure was identical to that found in hepatic growth factor (HGF), Han et al. proposed that the protein be called HGFL. The 2 proteins share about 50% sequence identity. To assess the in vivo effects of total loss of HGFL, Bezerra et al. generated mice with targeted disruption of the gene resulting in loss of the protein. Embryogenesis proceeded normally and followed a mendelian pattern of genetic transmission. Mice homozygous for the targeted allele, Hgfl -/- mice, were fertile and grew to adulthood without obvious phenotypic abnormalities in unchallenged animals, except for development of lipid-containing cytoplasmic vacuoles in hepatocytes throughout the liver lobules. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice