364178
MMP23B (Matrix Metalloproteinase 23B, MMP22, MMP23-B, MIFR, MIFR-1, Matrix Metalloproteinase 22, Femalysin, Matrix Metalloproteinase In The Female Reproductive Tract)
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£482.00
- SKU:
- 364178
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Tyr79-Gly390 of human MMP23B, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol
- Weitere Details:
- The gene for MMP-22 has been identified together with the gene for MMP-21 in the Cdc2L1-2 locus at the end of the short arm of human chromosome 1, 1p36.3, which is deleted frequently in a number of tumors (Gururajan et al, 1998). The gene has been renamed MMP-23B and its sequence is almost identical with that of MMP-21. The catalytic domain of MMP-22 is related most closely to MMP-11 (stromelysin-3). The protein does not contain a highly conserved cysteine residue in the proenzyme domain, shown to be involved in the autocatalytic activation of many metalloproteinases. Multiple MMP-22 mRNAs, some of which are derived by alternative splicing, are expressed in a tissue-specific manner. For other entries pertaining to metalloproteinases see also the Metalloproteinase Dictionary section of this encyclopedia. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 0.5-2ug/ml Immunohistochemistry (Paraffin): 5-20ug/ml Immunocytochemistry: 5-20ug/ml Optimal dilutions to be determined by the researcher. Positive Control Included: 364178A: MMP23B, Positive Control Suppled as a recombinant protein in loading buffer (100mM Tris, pH 6.8, 1% SDS, 150mM sodium chloride, 50mM DTT, 0.02% BPB, 0.02% sodium azide, 50% glycerol). DAB: 10ul/well ECL: 5ul/well Store at -20°C. Stable for 6 months after receipt. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap
- Versandbedingungen:
- Blue Ice