364037
MAG (Myelin Associated Glycoprotein, GMA, S-MAG, Siglec-4, SIGLEC4A, Sialic Acid Binding Ig-Like Lectin 4A)
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£482.00
- SKU:
- 364037
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Ser133-Lys237 of human MAG expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Weitere Details:
- Myelin-associated glycoprotein (MAG) is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins and is a functional ligand of the NOGO-66 receptor, NgR MAG is believed to be involved in myelination during nerve regeneration. Myelin-associated glycoprotein (MAG), a membrane protein of 100kD, is thought to be involved in the process of myelination (Barton et al., 1987). MAG is a sialic acid-binding SIGLEC protein and is a functional ligand for the NOGO receptor (NGR, or RTN4R) (Liu et al., 2002). Spagnol et al. (1989) found that MAG cDNA clones isolated from a human brain cDNA library had an open reading frame of 1878 nucleotides encoding a peptide of 626aa with a calculated molecular weight of 69.1kD. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice