LMAN2 (Lectin, Mannose Binding 2, GP36B, VIP36, C5orf8, Vesicular integral-membrane protein VIP36, Glycoprotein GP36b, Vesicular integral-membrane protein 36)

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£626.00

SKU:: 363981
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Asp45-Arg322 of human LMAN2 expressed in E. coli.
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Weitere Details:: By searching an EST database for sequences similar to dog Vip36, Neve et al. (2003) identified LMAN2, which they called VIP36. The deduced 356aa protein contains an N-terminal signal sequence, followed by a lectin-type carbohydrate recognition domain and a C-terminal transmembrane domain. A KRFY endoplasmic reticulum trafficking motif is located at the C-terminal. Northern blot analysis detected variable expression of 1.2- and 1.4kb VIP36 transcripts in all tissues examined. Highest expression was in kidney, placenta, and liver. Nufer et al. (2003) determined that the LMAN2 gene contains 8 exons and spans 14.9kb. By genomic sequence analysis, Nufer et al. (2003) mapped the LMAN2 gene to chromosome 5q35.5. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice