ITGaD (Integrin Alpha D, CD11d, CD11-D, ITG-AD, ADB2, ITGA-D, CD11 antigen-like family member D, Leukointegrin alpha D)

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£495.00

SKU:: 363784
Anwendung:: IHC-Fr
Reinheit:: Purified by Protein A and peptide affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to aa879-1099 of rat ITGaD expressed in E. coli.
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Weitere Details:: Three ITGs that share the beta-2 (CD18) subunit are restricted in expression to leukocytes and have homologous alpha subunits: alpha-L (ITGAL), alpha-M (ITGAM), and alpha-X (ITGAX). Wong designed degenerate PCR primers to identify novel leukocyte integrin alpha subunits. In this way they isolated a partial genomic clone encoding a new alpha subunit, designated ITGAD. The ITGAD gene was found to be highly homologous to the 3 previously known alpha-subunit-encoding genes in deduced aa sequence, intron/exon structure, and chromosomal location. The ITGAD gene localize to 16p11.2. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.01-2ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.