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363649

IL17RC (Interleukin 17 Receptor C, IL17-RL, IL17R-C, IL17Rhom, Interleukin-17 receptor homolog, Interleukin-17 receptor-like protein, ZcytoR14)

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£499.00

SKU:
363649
Reinheit:
Purified by Protein A and peptide affinity chromatography.
Lagerbedingungen:
-20°C
Hersteller:
United States Biological
Host:
Rabbit
Immunogen:
Recombinant protein corresponding to aa257-477 of human IL17RC, expressed in E. coli.
Format:
Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
Weitere Details:
Interleukin-17 receptor C is a single-pass transmembrane protein that shares limited similarity with the interleukin-17 receptor. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only three have been determined to date. The predicted full-length 720aa protein has an N-terminal signal peptide, followed by an acidic extracellular domain with 9 potential N-glycosylation sites, a single-pass transmembrane domain, and a basic cytoplasmic region with multiple phosphorylation sites. It has a calculated molecular mass of 76.4kD and shares 22%aa identity with IL17R.strongest expression in prostate, kidney, liver, heart, and muscle, with barely detectable levels in thymus and peripheral blood leukocytes. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 0.01-3ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Versandbedingungen:
Blue Ice