363638
IL16 (Interleukin 16, LCF, PrIL-16, Lymphocyte Chemoattractant Factor, Pro-Interleukin 16)
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£513.00
- SKU:
- 363638
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa508-627 of bovine IL16, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Weitere Details:
- IL-16 is constitutively expressed by both CD4+ and CD8+ T cells. Airway epithelium from asthmatics, eosinophils, and mast cells also produce IL-16, albeit only after stimulation. In lymphocytes, IL-16 is generated as a precursor molecule which is enzymatically cleaved following stimulation with T-cell mitogens. IL-16 is a proinflammatory and immunomodulatory cytokine. It is a potent chemoattractant for all CD4+ cells including T cells, monocytes, and eosinophils and, as such, has been identified at inflammatory sites characterized by infiltrating CD4+ cells.In addition to cell motility, IL-16 induces cell cycle progression and cytokine synthesis in CD4+ T cells. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunocytochemistry: 1:50-500 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice