GMCSF (Colony Stimulating Factor 2, Granulocyte Macrophage, CSF2, GM-CSF, Sargramostim, Molgramostin, Granulocyte-Macrophage Colony Stimulating Factor)

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£428.00

SKU:: 363321
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Ala18-Lys144 of rat GMCSF, expressed in E. coli.
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Weitere Details:: Granulocyte-macrophage colony stimulating factor (GM-CSF) was initially identified by its ability to stimulate the formation of granulocyte and macrophage colonies from hematopoietic progenitor cells in semi-solid media. In vivo and in vitro studies have now demonstrated that GM-CSF is a pleiotropic cytokine that induces myeloid precursor cells to proliferate and differentiate into neutrophils, monocyte/macrophages and eosinophils. GM-CSF has also been shown to stimulate the proliferation and differentiation of erythroid and megakaryocyte progenitor cells. In addition, GM-CSF is a survival factor for and activates the effector functions of mature neutrophils, monocytes/macrophages and eosinophils. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. AA Sequence: MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGSEF-APT RSPNPVTRPW KHVDAIKEAL SLLNDMRALE NEKNEDVDII SNEFSIQRPT CVQTRLKLYK QGLRGNLTKL NGALTMIASH YQTNCPPTPE TDCEIEVTTF EDFIKNLKGF LFDIPFDCWK PVQK Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice