363319
GLUT14 (Glucose Transporter 14, SLC2A14, GLUT3, Solute Carrier Family 2 Member 14, Facilitated Glucose Transporter)
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£626.00
- SKU:
- 363319
- Anwendung:
- WB
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Met1-Val105 of human GLUT14, expressed in E. coli.
- Format:
- Supplied as a liquid in 0.01M PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
- Weitere Details:
- Members of the glucose transporter (GLUT) family, including SLC2A14, are highly conserved integral membrane proteins that transport hexoses such as glucose and fructose into all mammalian cells. GLUTs show tissue and cell-type specific expression. By database analysis, followed by PCR of a human testis cDNA library, Wu and Freeze (2002) cloned SLC2A14. They identified 2 alternatively spliced forms. The short isoform has 10 exons and encodes a 497aa protein that shares 94.5% identity with SLC2A3. The long isoform has 11 exons and encodes a 520aa protein that differs from the short isoform by inclusion of exon 1b. SLC2A14 contains 12 transmembrane domains, a putative glycosylation site, and sugar transporter signature motifs. RT-PCR analysis showed that both isoforms were expressed in testis only. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice