363312
GLS2 (Glutaminase 2, GA, GLS, LGA, hLGA, L-glutaminase, L-glutamine amidohydrolase)
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£537.00
- SKU:
- 363312
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Ile154-Gly479 of mouse GLS2, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Weitere Details:
- GA encodes a deduced 602aa protein with a putative N-terminal mitochondrial import presequence. The GA protein shares 94% and 72% sequence identity with the rat liver and kidney glutaminase proteins, respectively. Using SDS-PAGE analysis, Gomez-Fabre et al. (2000) observed a purified fusion GA protein with an apparent molecular mass of 66kD. Northern blot analysis detected a 2.4-kb GA transcript in human liver, brain, and pancreas, but not in kidney, heart, skeletal muscle, lung, or placenta. Based on expression data and sequence homology, Gomez-Fabre et al. (2000) concluded that human GA is most similar to the rat liver-type glutaminase isoform, but is not liver specific as previously predicted from expression data of the rat kidney- and liver-type isoforms. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice