GKN1 (Gastrokine 1, CA11, AMP18, BRICD1, FOV, Foveolin, 18kD antrum mucosa protein)

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£626.00

SKU:: 363296
Reinheit:: Purified by Protein A and peptide affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Ala22-Asn199 of human GKN1, expressed in E. coli.
Format:: Supplied as a liquid in 0.01M PBS, pH7.4, 0.05% Proclin-300, 50% glycerol.
Weitere Details:: Gastrokine-1 is found to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa.Using differential display of normal and cancerous gastric tissue, followed by 5-prime RACE, Yoshikawa et al. (2000) identified cDNAs encoding CA11 and CAPN9. The deduced 199aa CA11 protein contains an asn-rich region. Northern blot analysis revealed expression of an approximately 1.1-kb CA11 transcript predominantly in stomach; no expression was detected in cancer tissue or gastric cancer cell lines. Yoshikawa et al. (2000) identified a marker in the CA11 gene that indicates a localization on chromosome 2. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.