FCN2 (Ficolin 2, EBP37, FCNL, P35, Hucolin, 37kD elastin-binding protein, Collagen/Fibrinogen Domain Containing Lectin, Ficolin B, Serum Lectin p35, L-Ficolin)

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£495.00

SKU:: 363087
Reinheit:: Purified by Protein A and peptide affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to aa97-254 of mouse FCN2, expressed in E. coli.
Format:: Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
Weitere Details:: Ficolin-2 belongs to the ficolin family of proteins. This family is characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. This gene is predominantly expressed in the liver, and has been shown to have carbohydrate binding and opsonic activities. Alternatively spliced transcript variants encoding different isoforms have been identified. Serum concentration of ficolin-2 varies considerably in healthy individuals.FCN2 promoter polymorphisms were associated with marked changes in the ficolin-2 serum concentration, whereas 2 nonsynonymous SNPsclustered in exon 8 encoding the fibrinogen-like domain were associated with decreased and increased GlcNAc binding, respectively. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 0.5-2ug/ml Immunohistochemistry (Paraffin): 5-20ug/ml Immunocytochemistry: 5-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice