363048
FAM20A (Family With Sequence Similarity 20, Member A)
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£626.00
- SKU:
- 363048
- Anwendung:
- WB
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa368-541 of human FAM20A, expressed in E. coli.
- Format:
- Supplied as a liquid in 0.01M PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
- Weitere Details:
- By database searching, they determined that this protein is a member of a family of related proteins with 2 other members in mammals: FAM20B and FAM20C. All FAM20 proteins contain putative conserved signal sequences as well as a conserved C-terminal domain. Fam20a-GFP fusion proteins displayed perinuclear and cytoplasmic staining consistent with localization in the endoplasmic reticulum. Transfection experiments in COS-1 cells demonstrated that Fam20a is a secreted glycoprotein, and immunofluorescence studies showed that an intact signal sequence is required for secretion. Examination of the expression pattern of FAM20A from a panel of cDNAs derived from various human tissues revealed high levels in lung and liver and intermediate levels in thymus and ovary. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice