CX3CL1 (Chemokine C-X3-C-Motif Ligand 1, NTN, ABCD3, C3Xkine, CXC3, CXC3C, NTT, SCYD1, ABCD3, FKN, Neurotactin, Fractalkine, Small Inducible Cytokine Subfamily D(Cys-X3-Cys)Member 1)

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£437.00

SKU:: 362762
Reinheit:: Purified by Protein A and peptide affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Gln83-Pro330 of mouse CX3CL1, fused to N-terminal His-Tag expressed in E. coli.
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Weitere Details:: CX3CL1 is the unique member of the CX3C chemokine subfamily. The membrane-anchored protein, which is primarily expressed on the inflamed endothelium, serves as an adhesion protein promoting the retention of monocytes and T cells in inflamed tissue. The soluble form resembles more a conventional chemokine and strongly induces chemotaxis. Both chemotaxis and adhesion are mediated by the G protein-coupled receptor CX3CR1. CX3CL1 has been thought to play an important role in inflammation, and indeed, accumulating evidence indicates that CX3CL1/CX3CR1 are involved in the pathogenesis of various inflammatory disorders such as glomerulonephritis, rheumatoid arthritis and systemic lupus erythematosus (SLE). Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:50-400 Immunocytochemistry: 1:50-500 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 ELISA: 1:100-1:5000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice