362739
CTL1 (Choline Transporter Like Protein 1,
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£524.00
- SKU:
- 362739
- Anwendung:
- WB
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Thr74-Cys183 of human CTL1, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Weitere Details:
- Using an expression cloning approach, Wille et al. (2001) obtained a cDNA encoding CDw92. The deduced 652aa CDw92 protein is 99% identical to the CTL1 protein reported by O'Regan et al. (2000). CDw92 has cytoplasmic N and C termini, 3 potential N-glycosylation sites, and a potential ITIM (immunoglobulin tyrosine-based inhibitory motif). Immunoprecipitation analysis showed that CDw92 is expressed as a 70kD protein. Flow cytometric analysis demonstrated expression of CDw92 on almost all B lymphocytes, most T lymphocytes, some NK cells, and some myeloid cell lines tested. Maturation of monocyte/dendritic cells resulted in downregulation of CDw92, and expression could subsequently be upregulated by interleukin-10 (IL10). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice