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362674

CRABP2 (Cellular Retinoic Acid Binding Protein 2, CRABP-II, RBP6)

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£626.00

SKU:
362674
Reinheit:
Purified by immunoaffinity chromatography.
Lagerbedingungen:
-20°C
Hersteller:
United States Biological
Host:
Rabbit
Immunogen:
Recombinant protein corresponding to Met1-Glu138 of human CRABP2, expressed in E. coli.
Format:
Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Weitere Details:
The inducibility of the CRABP2 gene suggests that this isoform is important in retinoic acid-mediated regulation of human skin growth and differentiation. It has been postulated that the CRABP2 gene is transcriptionally regulated by a newly synthesized regulatory protein. It was shown to be approximately 4.6 kb long and divided into 4 exons in a structure common to other members of the family of serum and cellular retinoid-binding proteins. The chromosomal location of the Crabp-2 locus was determined by interspecific backcross analysis using progeny derived from matings of C57BL/6J and M. spretus. Mapping results indicated that the gene is located on mouse chromosome 2 linked to muscle nicotinic acetylcholine receptor alpha-chain (Acra) and catalase-1 (Cas-1). Applications: Suitable for use in Western Blot, Immunohistochemistry and Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Versandbedingungen:
Blue Ice