CLU (Clusterin, TRPM2, KUB1, CLI, APOJ, SGP2, AAG4, APO-J, SP-40, Apolipoprotein J, Complement Lysis Inhibitor, 40,Sulfated Glycoprotein 2, Testosterone-Repressed Prostate Message 2)

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£523.00

SKU:: 362603
Anwendung:: WB
Reinheit:: Purified by Protein A and peptide affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Val223-Glu439 of bovine CLU expressed in E. coli.
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Weitere Details:: Clusterin (apolipoprotein J) is a 75 - 80kD disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. This protein has several synonyms: dimeric acidic glycoprotein (DAG protein), testosterone repressed prostate message-2 (TRPM-2), sulfated glycoprotein-2 (SGP-2) and complement lysis inhibitor (CLI). This protein was first identified in 1988 in seminal fluid.In humans the gene is encoded on chromosome 8 (8p21) and is highly conserved between species (70-80% homology).It is expressed in most mammalian tissues and can be found in blood plasma, milk, urine, cerebrospinal fluid and semen. A number of proteins have been found to affect its expression including Egr-1, members from the AP-1 complex, HSF1/2, Cdx1/2 and B-Myb. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- VMPFPLLE PFNFHDVFQP FYDMIHQAQQ AMDAHLQRTP YHFPTMEFTE NNDRTVCKEI RHNSTGCLRM KDQCEKCQEI LEVDCSASNP TQTLLRQQLN ASLQLAEKFS RLYDQLLQSY QQKMLNTSAL LKQLNEQFTW VSQLANLTQS DDQHYLQVFT VNSHNSDPSI PSGLTKVIVK LFNSFPITVT VPQEVSSPNF MENVAEKALQ QYRRKSQEE Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice