CLEC13A (C-Type Lectin Domain Family 13, Member A, CD302, CLEC13-A, DCL-1, BIMLEC, C-type lectin BIMLEC, DEC205-associated C-type lectin 1, Type I transmembrane C-type lectin receptor DCL-1)

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£524.00

SKU:: 362593
Anwendung:: WB
Reinheit:: Purified by Protein A and peptide affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Asp23-Asp232 of human CLEC13A expressed in E. coli.
Format:: Supplied as a liquid in 0.01M PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
Weitere Details:: CD302 is a C-type lectin receptor involved in cell adhesion and migration, as well as endocytosis and phagocytosis. By sequencing clones obtained from a size-fractionated immature myeloid leukemia cell line cDNA library, Nomura et al. (1994) obtained a partial cDNA encoding CD302, which they called KIAA0022. Northern blot analysis revealed variable expression of a 4.2-kb CD302 transcript in all tissues examined, with highest levels in lung, liver, ovary, and peripheral blood. By 3-prime RACE analysis of DEC205 (LY75) in a Hodgkin and Reed-Sternberg (HRS) lymphoma cell line, Kato et al. (2003) identified a cDNA encoding a fusion of DEC205 with CD302, which they called DCL1. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- DCPSSTWI QFQDSCYIFL QEAIKVESIE DVRNQCTDHG ADMISIHNEE ENAFILDTLK KQWKGPDDIL LGMFYDTDDA SFKWFDNSNM TFDKWTDQDD DEDLVDTCAF LHIKTGEWKK GNCEVSSVEG TLCKTAIPYK RKYLSDNHIL ISALVIASTV ILTVLGAIIW FLYKKHSDSR FTTVFSTAPQ SPYNEDCVLV VGEENEYPVQ FD Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice