CLEC10A (C-Type Lectin Domain Family 10, Member A, CD301, CLEC10-A, CLECSF13, CLECSF14, Macrophage Lectin 2(Calcium Dependent), C-type lectin superfamily member 14, Macrophage lectin 2)

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£495.00

SKU:: 362589
Reinheit:: Purified by Protein A and peptide affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Arg69-Asp273 of mouse CLEC10A expressed in E. coli.
Format:: Supplied as a liquid in 0.01M PBS, pH7.4, 0.05% Proclin-300, 50% glycerol.
Weitere Details:: C-type lectin domain family 10, member A also known as CLEC10A is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene.Sequence analysis predicted that the 292aa type II transmembrane protein has a cytoplasmic domain with a tyr-glu-asn-phe (YENF) internalization signal, a transmembrane domain, a neck domain, and a C-type lectin domain containing a gln-pro-asp motif. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- RA TLDNTTSKIK AEFQSLDSRA DSFEKGISSL KVDVEDHRQE LQAGRDLSQK VTSLESTVEK REQALKTDLS DLTDHVQQLR KDLKALTCQL ANLKNNGSEV ACCPLHWTEH EGSCYWFSES EKSWPEADKY CRLENSHLVV VNSLEEQNFL QNRLANVVSW IGLTDQNGPW RWVDGTDFEK GFKNWAPLQP DNWFGHGLGG GED Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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