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362571

CHRNb2 (Cholinergic Receptor, Nicotinic, Beta 2, CHR-NB2, CHRN-B2, EFNL3, NAChRB2, N-AChR-B2, N-AChRB2, Neuronal Acetylcholine Receptor Beta 2)

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£524.00

SKU:
362571
Reinheit:
Purified by immunoaffinity chromatography.
Lagerbedingungen:
-20°C
Hersteller:
United States Biological
Host:
Rabbit
Immunogen:
Recombinant protein corresponding to Trp24-Val70 and Glu86-Pro244 of human CHRNb2, expressed in E. coli.
Format:
Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Weitere Details:
CHRNB2 encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy. The CHRNB2 gene comprises 6 exons and spans approximately 9 kb of genomic DNA from the ATG start codon to the TGA stop codon. Exon 1 contains the 5-prime untranslated region, the ATG start codon, and parts of the sequence coding for the putative signal peptide. The hydrophobic transmembrane domains I through III are located in the large exon 5. Exon 6 contains the transmembrane domain IV as well as the translation stop codon and the 3-prime untranslated region. The CHRNB2 introns vary in size from 150 bp (intron 2) to 4.5 kb (intron 5). The splicing at the junctions of CHRNB2 introns 2, 3, and 5 occurred between codons (splicing type 0). Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Versandbedingungen:
Blue Ice