362441
CD109 (Differentiation 109, CPAMD7, p180, r150, Gov platelet alloantigens, 150kD TGF-beta-1-binding protein, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7)
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£524.00
- SKU:
- 362441
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Ala1146-Gln1390 of human CD109 expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Weitere Details:
- CD109 is a GPI-linked cell surface antigen expressed by CD34 acute myeloid leukemia cell lines, T-cell lines, activated T lymphoblasts, endothelial cells, and activated platelets (Lin et al., 2002). In addition, the platelet-specific Gov antigen system, implicated in refractoriness to platelet transfusion, neonatal alloimmune thrombocytopenia, and posttransfusion purpura, is carried by CD109 (Kelton et al., 1990; Lin et al., 2002). CD109 encodes a deduced 1,445aa protein with a predicted molecular mass of approximately 162kD. The protein contains a cleavable 21 residue N-terminal sequence, 17 potential N-linked glycosylation sites, a GPI anchor site, and a thioester motif characteristic of the alpha-2- macroglobulin (A2M)/complement (AMCOM) family. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice