362266
Bcl3 (B-Cell CLL/Lymphoma 3, BCL4, B-Cell Lymphoma 3-Encoded Protein, B-Cell Lymphoma 3-Encoded Protein, Chronic Lymphatic Leukemia Protein, Proto-oncogene BCL3)
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£495.00
- SKU:
- 362266
- Anwendung:
- WB
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa82-341 of mouse Bcl3, expressed in E. coli.
- Format:
- Supplied as a liquid in 0.01M PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
- Weitere Details:
- B-cell lymphoma 3-encoded protein is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional coactivator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.Wulczyn et al. (1992) and Franzoso et al. (1992) found that the BCL3 gene encodes an inhibitor (antagonist) for subunit 2 of nuclear factor kappa-B (NFKB2). Applications: Suitable for use in ELISA, Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 0.5-2ug/ml IOptimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice