362169
APPBP2 (Amyloid Beta Precursor Protein Binding Protein 2, PAT1, Protein Interacting With APP Tail 1,Cytoplasmic Tail, Amyloid protein-binding protein 2, Protein interacting with APP tail 1)
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£577.00
- SKU:
- 362169
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Lys396-Cys585 of rat APPBP2, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Weitere Details:
- APPBP2is a protein interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. APPBP2 is present as a 70kD protein in both cytosolic and, together with APP, membrane-associated cell fractions. Immunofluorescence microscopy demonstrated that APPBP2 is present in the Golgi region and that its distribution overlaps that of APP. APPBP2 interacts with microtubules and is functionally associated with APP transport and/or processing. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice