APOH (Apolipoprotein H, Apo-H, B2G1, BG, B2-GP1, B2GP1, Previously, Beta 2 Glycoprotein 1, APC inhibitor, Activated protein C-binding protein, Anticardiolipin cofactor, Beta(2)GPI)

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£495.00

SKU:: 362163
Reinheit:: Purified by Protein A and peptide affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Gly20-Cys297 of rat APOH, expressed in E. coli.
Format:: Supplied as a liquid in 0.01M PBS, pH7.4, 0.05% Proclin-300, 50% glycerol.
Weitere Details:: Apolipoprotein H (ApoH), also known as Beta 2-glycoprotein I, is a plasma glycoprotein either circulating as a free protein or associated to lipoproteins. This protein was found in human serum and described for the first time in 1961 by Schultze et al. ApoH is a 54kD single-chain glycoprotein consisting of five carbohydrate chains and 326aa residues that can be divided into five short consensus repeat domains. ApoH has been chiefly focused on as the cofactor or autoantigen in antiphospholipid syndrome (APS), which is related to venous and arterial thrombosis, fetal loss, and thrombocytopenia. Reports show that ApoH may have an important function in blood coagulation and clearance of apoptotic bodies from the circulation Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- G RRMWPINTLK CTPRVCPFAG ILENGVVRYT TFEYPNTIGF ACNPGYYLNG TSSSKCTEEG KWSPELPVCA RITCPPPPIP KFAALKEYKT SVGNSSFYQD TVVFKCLPHF AMFGNDTVTC TAHGNWTQLP ECREVKCPFP SRPDNGFVNY PAKPVLSYKD KAVFGCHETY KLDGPEEVEC TKTGNWSALP SCKASCKLSV KKATVLYQGQ RVKIQDQFKN GMMHGDKVHF YCKNKEKKCS YTEEAQCIDG TIEIPKCFKE HSSLAFWKTD ASDVTPC Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice