362120
ANKRD1 (Ankyrin Repeat Domain Protein 1, CARP, ALRP, C-193, CVARP, MCARP, Ankyrin Repeat Domain 1(Cardiac Muscle), Cardiac ankyrin repeat protein, Cytokine-inducible gene C-193, Cytokine-inducible nuclear protein)
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£537.00
- SKU:
- 362120
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Met1-Phe319 of mouse ANKRD1, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Weitere Details:
- Expression of MARPs is induced in response to physiologic stress, injury, and hypertrophy. The deduced 319aa protein has a calculated molecular mass of 36kD. ANKRD1 contains a nuclear localization signal, 4 tandem ankyrin-like repeats, multiple phosphorylation sites, and a PEST-rich region, which is typically found in rapidly degraded proteins. The 3-prime UTR of ANKRD1 has numerous AT-rich mRNA decay elements. Northern blot analysis of multiple human cell lines detected ANKRD1 expression in microvascular and large vessel endothelial cell lines. Immunofluorescence of transfected COS cells and immunoprecipitation of nuclear and cytoplasmic extracts of COS cells showed that ANKRD1 was abundantly expressed in nucleus. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice