A Disintegrin And Metalloprotease 1 (FTNAP, PH-30a, Ftna, ADAM1P, Fertilin Alpha, Disintegrin and metalloproteinase domain-containing protein 1)

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£563.00

SKU:: 361929
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to aa463-727 of rat ADAM1, expressed in E. coli.
Format:: Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
Weitere Details:: ADAM is a family of peptidase proteins. It is also known as the adamalysin family. ADAMs are classified as sheddases because they cut off or shed extracellular portions of transmembrane proteins. The human fertilin alpha gene is non-functional: implications for its proposed role in fertilization.In the guinea-pig, the alpha subunit of the fertilin complex, a heterodimeric surface membrane glycoprotein found on the head region of spermatozoa, has previously been proposed to mediate membrane fusion with the oolemma plasma membrane during fertilization. The only fertilin alpha-like gene in humans is an expressed, but nonfunctional, pseudogene, possibly derived by genetic recombination between the two fertilin alpha genes found in some primates. This finding clearly raises questions about the importance and/or role of fertilin alpha in mammalian fertilization. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 5-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice