361580
EGFR (ERBB, ERBB1, HER1, PIG61, mENA, Avian Erythroblastic Leukemia Viral (v-erb-b) Oncogene Homolog, Cell Growth Inhibiting Protein 40, Cell Proliferation-inducing Protein 61, Proto-oncogene c-ErbB-1, Receptor Tyrosine-protein Kinase erbB-1, Epidermal Growth Factor) (Chimeric)
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£840.00
- SKU:
- 361580
- Reinheit:
- Purified by Protein A affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Partially purified EGFR from A431 cells.
- Klon:
- 528 (recomb)
- Format:
- Supplied as a liquid in PBS, pH 7.2, 0.02% Proclin-300.
- Weitere Details:
- Recombinant monoclonal antibody to EGFR with variable regions (i.e. specificity) from the hybridoma 528). This chimeric rabbit antibody was made using the variable domain sequences of the original mouse IgG2a format. Manufactured using a proprietary recombinant platform technology. The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Applications: Suitable for use in Immunofluorescence, Flow Cytometry, Western Blot, Immunoprecipitation, Immunohistochemistry (paraffin) and Neutralization. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice