EGFR (ERBB, ERBB1, HER1, PIG61, mENA, Avian Erythroblastic Leukemia Viral (v-erb-b) Oncogene Homolog, Cell Growth Inhibiting Protein 40, Cell Proliferation-inducing Protein 61, Proto-oncogene c-ErbB-1, Receptor Tyrosine-protein Kinase erbB-1, Epidermal Growth Factor)

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£674.00

SKU:: 361574
Reinheit:: Purified by Protein A affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to the extracellular domain of mouse EGFR (rECD-mEGFR).
Klon:: 7A7 (recomb)
Format:: Supplied as a liquid in PBS, pH 7.2, 0.02% Proclin-300.
Weitere Details:: Recombinant monoclonal antibody to EGFR with variable regions (i.e., specificity) from the hybridoma 7A7. Manufactured using a proprietary recombinant platform technology. The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. Applications: Suitable for use in Immunofluorescence, Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice