353439
SUMO-1 (SMT3, GMP1, UBL1, PIC1)
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£845.00
- SKU:
- 353439
- Reinheit:
- Purified by Protein G affinity chromatography.
- Lagerbedingungen:
- 4°C Do Not Freeze
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- hSUMO-1 and Lipoplex (O) complex
- Klon:
- 1B12-E2
- Format:
- Supplied as a liquid in PBS, 1% BSA, 0.02% sodium azide.
- Weitere Details:
- Post-translational modification regulated by conjugation of a small ubiquitin-like modifier (SUMO) is involved in various cellular processes such as transcriptional regulation, apoptosis and nuclear transport. Recent proteomic analyses in mammalian cells revealed that a number of SUMO substrates and specific modifications by SUMO-1 are involved in essential processes, including chromatin organization, transcription, RNA metabolism, immunomodulation and development of the innate immune system. Higher expression of SUMO-1 was detected in normal adrenal gland, esophagus, pancreas, liver, stomach, kidney, and uterus. the function of SUMO-1 may vary depending on the tissue types. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: A non-reduced sample treatment was used. Immunohistochemistry (paraffin): Tissue sections were deparaffinized in xylene, rehydrated, and treated with fresh 0.3% hydrogen peroxide in methanol for 15 min Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice