SPINSTER, NT (LAT, Nrs, SPIN1, SPINL, HSpin1, PP2030, PP20300, Protein spinster homolog 1)

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£655.00

SKU:: 352552
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Peptide corresponding to 18aa near the N-terminal of human SPINSTER.
Format:: Supplied as a liquid in PBS, 0.02% sodium azide.
Weitere Details:: SPINSTER, also known as SPNS1 or SPIN1, is a 528aa multi-pass membrane protein that localizes to the inner mitochondrial membrane and belongs to the spinster subfamily of the major facilitator superfamily (1). SPINSTER interacts with Bcl-x and Bcl-2 and, via this interaction, is thought to be involved in necrotic or autophagic cell death (2). The related protein SPNS2 is critical for the normal lymphocyte localization and mammalian immune system function (1,3). Applications: Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunofluorescence: 20ug/ml Western Blot: 1-2ug/ml Immunohistochemistry (paraffin): 2.5ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human Placenta Tissue Lysate Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.