NKIRAS2, Recombinant, Human, aa1-191, His-Tag (NFKB inhibitor interacting Ras-like 2, kappaB-Ras2, KBRAS2)

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£512.00

SKU:: 351391
Molekulargewicht:: 24
Reinheit:: ≥90% (SDS-PAGE)
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Format:: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 0.1M sodium chloride, 10% glycerol.
Weitere Details:: NFKB inhibitor interacting Ras-like 2 (NKIRAS2), also known as KBRAS2, is similar to the Ras-like small GTPases that associate with IkappaB. These Ras-like proteins, NKIRAS1 and NKIRAS2, interact with the PEST domains of IkBa and IkBb and decrease their rate of degradation. NKIRAS2 shows 71% identity to KBRAS1. NKIRAS2 is an inhibitor of the transcription factor NF-kappaB. Recombinant protein corresponding to aa1-191 from human NKIRAS2, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~24kD (215aa) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMGKSCK VVVCGQASVG KTSILEQLLY GNHVVGSEMI ETQEDIYVGS IETDRGVREQ VRFYDTRGLR DGAELPRHCF SCTDGYVLVY STDSRESFQR VELLKKEIDK SKDKKEVTIV VLGNKCDLQE QRRVDPDVAQ HWAKSEKVKL WEVSVADRRS LLEPFVYLAS KMTQPQSKSA FPLSRKNKGS GSLDG Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.