IL17A, Recombinant, Human, aa24-155, His-Tag (Interleukin 17, CTLA8, IL-17, IL-17A, IL17)

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£448.00

SKU:: 351305
Molekulargewicht:: 15.9
Reinheit:: ≥95% (SDS-PAGE). Endotoxin: ≤1EU/ug (LAL).
Lagerbedingungen:: -20°C/-70°C
Hersteller:: United States Biological
Format:: Supplied as a liquid in PBS, pH 7.4, 1mM EDTA, 0.1mM PMSF, 20% glycerol.
Weitere Details:: IL17A, also known as Interleukin 17, is a cytokine that acts as a potent mediator in delayed-type reactions by increasing chemokine production in various tissues to recruit monocytes and neutrophils to the site of inflammation. It is produced by T-helper cells and is induced by IL23 which results in destructive tissue damage in delayed-type reactions. This protein is a 155aa protein that is a disulfide-linked, homodimeric, secreted glycoprotein with a molecular mass of 35kD. The structure of IL17A consists of a signal peptide of 23aas followed by a 123aa chain region characteristic of the IL17 family. An N-linked glycosylation site on the protein was first identified after purification of the protein revealed two bands, one at 15kD and another at 20kD. Source: Recombinant protein corresponding to aa24-155 from human IL17A, fused to His-tag at C-terminal expressed in insect cell. Molecular Weight: ~15.9kD(138aa) Amino Acid Sequence: GITIPRNPGC PNSEDKNFPR TVMVNLNIHN RNTNTNPKRS SDYYNRSTSP WNLHRNEDPE RYPSVIWEAK CRHLGCINAD GNVDYHMNSV PIQQEILVLR REPPHCPNSF RLEKILVSVG CTCVTPIVHH VAHHHHHH Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Versandbedingungen:: Blue Ice