NAT8L, NT (N-acetylaspartate synthetase, NAA synthetase, 2.3.1.17, Camello-like protein 3, N-acetyltransferase 8-like protein, CML3)

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£384.00

SKU:: 350463
Reinheit:: Purified by Protein A and peptide affinity chromatography
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 59-93 in the N-terminal region of human NAT8L. Species Sequence Homology: mouse and rat
Format:: Supplied as a liquid in PBS, 0.09% sodium azide
Weitere Details:: Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Immunohistochemistry (Paraffin): 1:250. Heat induced epitope retrieval with EDTA Buffer, pH 9.0 is recommended. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.