Interleukin-1 alpha, active (Il1a), Recombinant, Mouse

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£518.00

SKU:: 348090
Molekulargewicht:: 17.9
Reinheit:: ≥97% as determined by SDS-PAGE and HPLC.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Format:: Lyophilized from 0.2um filtered PBS, pH 7.4
Weitere Details:: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 2 pg/ml, corresponding to a specific activity of ＞ 5.0x10e8 IU/mg. Sequence: SAPYTYQSDL RYKLMKLVRQ KFVMNDSLNQ TIYQDVDKHY LSTTWLNDLQ QEVKFDMYAY SSGGDDSKYP VTLKISDSQL FVSAQGEDQP VLLKELPETP KLITGSETDL IFFWKSINSK NYFTSAAYPE LFIATKEQSR VHLARGLPSM TDFQIS Molecular Weight: 17.9kD PubMed ID: 6209582; 15489334; 3126184 Gene Name: Il1a Swiss Prot: P01582 Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.