348045
Fibroblast Growth Factor 21, active (FGF21), Recombinant, Human
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£411.00
- SKU:
- 348045
- Molekulargewicht:
- 19.4
- Reinheit:
- ≥96% as determined by SDS-PAGE and HPLC.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Format:
- Lyophilized from 0.2um filtered PBS, pH 7.4
- Weitere Details:
- Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5ug/ml, corresponding to a specific activity of ＞ 2.0x10e3 IU/mg in the presence of 5ug/ml of rMuKlotho-β and 10ug/ml of heparin. Sequence: HPIPDSSPLL QFGGQVRQRY LYTDDAQQTE AHLEIREDGT VGGAADQSPE SLLQLKALKP GVIQILGVKT SRFLCQRPDG ALYGSLHFDP EACSFRELLL EDGYNVYQSE AHGLPLHLPG NKSPHRDPAP RGPARFLPLP GLPPALPEPP GILAPQPPDV GSSDPLSMVG PSQGRSPSYA S Molecular Weight: 19.4kD PubMed ID: 10858549; 12975309; 15489334; 15340161; 15902306; 17623664; 18829467; 19117008; 20094046 Gene Name: FGF21, UNQ3115/PRO10196 Swiss Prot: Q9NSA1 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice